pyridoxal 5 phosphate powder
Pyridoxal 5-Phosphate, commonly known as P5P, is the metabolically active coenzyme form of vitamin B6. Unlike other forms of vitamin B6 such as pyridoxine HCl, this p5p powder is immediately ready for use by the body’s enzyme systems without requiring prior conversion in the liver. This makes P5P an exceptionally bioavailable and effective form of the vitamin. The primary benefits of P5P are extensive and crucial for numerous physiological processes, including amino acid metabolism, neurotransmitter synthesis (like serotonin and dopamine), red blood cell formation, and immune function. Its vital role in over 100 enzymatic reactions makes this p5p powder an indispensable ingredient in high-quality nutritional supplements targeting nervous system support, energy metabolism, and overall well-being.
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- CAS No.: 54-47-7
- Chemical Name: Pyridoxal 5′-phosphate
- Synonyms: P5P; Pyridoxal phosphate; Codecarboxylase; Pyridoxal-5-phosphate; Vitamin B6 phosphate
- CB Number: CB9194218
- Molecular Formula:
- Molecular Weight: 247.14 g/mol
- MDL Number: MFCD00008409
Pyridoxal 5-Phosphate Manufacturing Process
Pyridoxine HCl Sourcing & Preparation
High-purity pyridoxine hydrochloride (vitamin B6 HCl) is obtained as the starting material. This form of vitamin B6 serves as the precursor for the synthesis of pyridoxal 5-phosphate. Quality checks ensure its initial purity.
Phosphorylation Reaction
Pyridoxine HCl undergoes a phosphorylation reaction, typically involving a phosphorylating agent such as phosphorus oxychloride or similar compounds. This process adds a phosphate group to the pyridoxine molecule.
Oxidation to Pyridoxal
The phosphorylated pyridoxine derivative is then subjected to a controlled oxidation step. This converts the hydroxymethyl group at the 4-position to an aldehyde group, resulting in the formation of pyridoxal 5-phosphate.
Purification & Isolation
Multi-stage purification methods are employed to isolate pure pyridoxal 5-phosphate. This typically includes chromatography, crystallization, and filtration steps to remove unreacted materials, by-products, and impurities, ensuring high purity of the P5P powder.
Drying & Milling
The purified pyridoxal 5-phosphate is carefully dried, often using vacuum drying or spray drying, to remove residual solvents and moisture. The dried product is then milled to a fine, consistent powder, suitable for various applications and ensuring uniform particle size.
Quality Control & Packaging
The final pyridoxal 5-phosphate powder undergoes rigorous quality control testing for purity, potency, solubility, heavy metals, and other specifications. Once approved, it is carefully packaged in light-resistant, airtight containers, often with inert gas, to maintain stability and extend shelf life before distribution.
Why Choose Gensei as Your Pyridoxal 5-Phosphate Supplier?
Choosing Gensei as your Pyridoxal 5-Phosphate supplier ensures access to a leading manufacturer committed to excellence. We understand the critical importance of P5P as the active form of vitamin B6, delivering superior bioavailability and direct physiological impact compared to conventional pyridoxine HCl. Our state-of-the-art manufacturing processes guarantee unparalleled purity and potency in every batch of pyridoxal 5 phosphate powder, maximizing its extensive benefits for neurological support, energy metabolism, and more. With Gensei, you gain a reliable partner with a robust supply chain, stringent quality control, and dedicated customer service, ensuring your products leverage the full potential of high-quality P5P powder to meet market demands.
Features of Pyridoxal 5-Phosphate:
- Active Coenzyme Form: Directly usable by the body’s enzymes, eliminating the need for metabolic conversion, enhancing efficiency.
- Superior Bioavailability: Offers better absorption and utilization compared to pyridoxine HCl, especially for individuals with compromised conversion abilities.
- Crucial for Enzymatic Reactions: Acts as a coenzyme for over 100 enzymatic reactions in the body, vital for metabolism and nervous system function.
- High Purity P5P Powder: Manufactured to stringent quality standards, ensuring a pure and potent ingredient for sensitive applications.
- Enhanced Stability: Our P5P powder is produced and packaged to maintain its stability and effectiveness over time.
Application Scenarios of Pyridoxal 5-Phosphate:
- Dietary Supplements: A premium ingredient in B-complex formulas, nerve support supplements, and mood-enhancing products, capitalizing on P5P’s extensive benefits.
- Neurological Support: Used in formulations aimed at supporting brain health, cognitive function, and neurotransmitter balance.
- Energy Metabolism: Essential for the breakdown of carbohydrates, fats, and proteins, making it valuable in energy and athletic performance supplements.
- Detoxification Support: Plays a role in liver detoxification pathways, often included in detox and liver support formulas.
- Pharmaceutical & Medical Foods: Utilized in specific therapeutic applications where optimized vitamin B6 delivery is critical, such as certain genetic metabolic disorders.
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FAQs
P5P, or pyridoxal 5-phosphate, is the active coenzyme form of vitamin B6, meaning it's the form that the body can directly use for metabolic functions without needing to be converted.
The main benefits of p5p powder include its crucial role in amino acid metabolism, neurotransmitter synthesis (like serotonin and dopamine), red blood cell formation, and supporting healthy immune function and cognitive health.
P5P is often considered superior because it is the biologically active form, which means it can be immediately utilized by the body. Standard pyridoxine HCl needs to be converted into P5P in the liver, a process that can be inefficient in some individuals.
Yes, P5P plays a vital role in the synthesis of several neurotransmitters, including serotonin, dopamine, and GABA, which are crucial for mood regulation, sleep, and overall neurological health.
P5P is generally well-tolerated at recommended doses. High doses of standard pyridoxine HCl can sometimes lead to nerve issues, but P5P is less likely to cause such issues due to its pre-activated form. Always follow dosage instructions.
P5P is a coenzyme for many enzymes involved in the metabolism of carbohydrates, fats, and proteins, helping the body convert food into usable energy.
P5P powder is frequently found in high-quality dietary supplements, B-complex formulas, nerve support supplements, prenatal vitamins, and formulations targeting mood and sleep support.
Yes, pyridoxal 5-phosphate is typically synthesized and is suitable for both vegan and vegetarian diets.
The recommended dosage for P5P can vary depending on individual needs and health goals, typically ranging from 10 mg to 50 mg daily in supplements. It's always best to consult with a healthcare professional for personalized advice.
P5P powder should be stored in a cool, dark, and dry place, away from direct sunlight and moisture, in an airtight container to preserve its stability and potency.
