Calcium Folate Manufacturer

Calcium Folate

calcium folate powder

Calcium Folate, chemically known as L-5-methyltetrahydrofolate calcium salt, is the active and readily usable form of folate. Unlike synthetic folic acid, which requires multiple enzymatic steps to be converted into its active form, calcium folate is directly utilized by the body, making it highly bioavailable. This vital nutrient plays a critical role in numerous physiological processes, particularly DNA synthesis, cell division, and red blood cell formation. The benefits of calcium folate are extensive, including supporting healthy fetal development during pregnancy, aiding in neurotransmitter synthesis, and contributing to cardiovascular health by helping to regulate homocysteine levels. Its superior absorption makes calcium folate powder an essential ingredient in high-quality prenatal supplements, B-complex formulas, and products targeting methylation support.

Please note: We are a wholesale supplier and have minimum order quantities.

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  • CAS No.: 151533-22-1
  • Chemical Name: L-5-methyltetrahydrofolate calcium
  • Synonyms: L-Methylfolate Calcium; Levomefolate Calcium; 5-MTHF Calcium; Metafolin (trademarked form, often used synonymously in industry discussions); Active Folate Calcium Salt
  • CB Number: CB5860710
  • Molecular Formula: (for the calcium salt form, note a specific number of waters of hydration may be present, e.g., dihydrate)
  • Molecular Weight: 497.51 g/mol (for the anhydrous form)
  • MDL Number: MFCD00269389
Calcium Folate Manufacturing Process

Calcium Folate Manufacturing Process

1

Folic Acid Sourcing & Reduction

High-purity synthetic folic acid serves as the primary starting material. This compound undergoes a controlled chemical reduction process to form tetrahydrofolate derivatives, a crucial step towards creating the active folate form.

2

Methylation to L-5-Methyltetrahydrofolate

The tetrahydrofolate derivative is then specifically methylated, typically involving a methylating agent. This reaction forms L-5-methyltetrahydrofolate (5-MTHF), which is the bioactive form of folate found naturally in the body.

3

Salt Formation with Calcium

The L-5-methyltetrahydrofolate is then reacted with a high-purity calcium source (e.g., calcium carbonate or calcium chloride) to form L-5-methyltetrahydrofolate calcium salt. This renders the active folate stable for commercial applications.

4

Purification & Crystallization

Extensive purification stages are employed to remove impurities, unreacted materials, and by-products. This often includes filtration, washing, and controlled crystallization processes to ensure the high purity and consistent crystalline structure of the calcium folate powder.

5

Drying & Milling

The purified calcium folate crystals are carefully dried using precise techniques, such as vacuum drying, to remove all residual moisture. The dried product is then milled to achieve a fine, uniform powder consistency, essential for various applications.

6

Quality Control & Packaging

The final calcium folate powder undergoes rigorous quality control testing for purity, potency, solubility, heavy metals, and other critical specifications. Once approved, it is meticulously packaged in airtight, light-resistant containers, often under inert gas, to protect its integrity and extend shelf life before distribution.

Why Choose Gensei as Your Calcium Folate Supplier?

Choosing Gensei as your calcium folate supplier guarantees access to a high-quality, bioavailable form of folate crucial for your products. We specialize in manufacturing premium calcium folate powder, ensuring the L-5-methyltetrahydrofolate calcium salt is of exceptional purity and stability. Our commitment to rigorous quality control processes ensures that every batch delivers optimal benefits of calcium folate, directly supporting DNA synthesis, cell division, and overall health. We understand the critical importance of this active nutrient, particularly for prenatal and methylation support supplements. Partner with Gensei for a reliable supply, expert technical assistance, and a dedication to excellence that sets your formulations apart by leveraging the full potential of calcium folate.

Features of Calcium Folate:

  • Highly Bioavailable: Directly usable form of folate (L-5-methyltetrahydrofolate calcium salt), bypassing the need for metabolic conversion.
  • Superior Stability: The calcium salt form offers enhanced stability compared to other active folate forms, making it ideal for various formulations.
  • Essential for Methylation: Crucial for the methylation cycle, supporting numerous biochemical processes including detoxification and neurotransmitter synthesis.
  • Key for Pregnancy: Plays a vital role in healthy fetal development, particularly in preventing neural tube defects.
  • Pure Calcium Folate Powder: Manufactured to stringent quality standards, ensuring a high-purity ingredient suitable for sensitive applications.

Application Scenarios of Calcium Folate:

  • Prenatal Vitamins: A preferred and essential ingredient in prenatal supplements due to its direct bioavailability and critical role in fetal development.
  • B-Complex Supplements: Included in high-quality B-complex formulas for comprehensive metabolic and neurological support.
  • Methylation Support Products: Utilized in supplements designed to optimize methylation pathways, beneficial for genetic predispositions (e.g., MTHFR variations).
  • Cardiovascular Health Supplements: Helps maintain healthy homocysteine levels, contributing to cardiovascular well-being.
  • General Health & Wellness: Incorporated into multivitamin formulations to support DNA synthesis, cell division, and overall cellular health.

Our State-of-the-Art Manufacturing Facilities

Explore our modern facilities equipped with advanced technology to ensure the highest quality in the production of your vitamins, herbal extracts, minerals, and amino acids.

FAQs

Calcium folate is the calcium salt of L-5-methyltetrahydrofolate, which is the active and naturally occurring form of folate. It's often referred to as L-methylfolate calcium.

Folic acid is a synthetic form of folate that requires conversion in the body to its active form (L-5-methyltetrahydrofolate). Calcium folate is already in this active form, making it directly usable by the body without conversion.

The main benefits include supporting DNA synthesis and repair, cell division, red blood cell formation, neurotransmitter production, and helping to regulate homocysteine levels, which is important for cardiovascular health.

Calcium folate is crucial for healthy fetal development, especially for preventing neural tube defects. Its active form ensures efficient utilization by both the mother and the developing fetus.

Yes, calcium folate is significantly more bioavailable than folic acid because it is already in the active form (5-MTHF) that the body uses. This is particularly beneficial for individuals with MTHFR genetic variations.

Yes, folate is involved in the synthesis of neurotransmitters like serotonin, dopamine, and norepinephrine, which play key roles in mood regulation and cognitive function. Active calcium folate can support these processes.

Calcium folate is generally well-tolerated at recommended doses. Side effects are rare, but as with any supplement, excessive intake could potentially lead to mild digestive upset.

Calcium folate powder should be stored in a cool, dry place, away from light and moisture, in an airtight container to maintain its stability and potency.

Yes, calcium folate is generally suitable for vegans and vegetarians as it is produced synthetically and does not involve animal-derived ingredients.

Dosages can vary, but common amounts in supplements range from 400 mcg DFE (Dietary Folate Equivalents) to 1000 mcg DFE or more, depending on the specific health goal (e.g., prenatal, methylation support).

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